Dr. Daniel Sipple
Doctor of Osteopathic Medicine
Sipple Medical Innovations, LLC
Sipple Medical Innovations, LLC
2233 Hamline AvenueSuite 611Roseville, Minnesota, 55113USAAbout
- Physician with extensive experience in rehabilitation medicine, interventional pain, spine care, and medical innovation
- Began career on faculty at Shirley Ryan Ability Lab, consistently ranked the top rehabilitation hospital in the U.S. by U.S. News & World Report
- Staffed the Shirley Ryan Ability Lab Pain Center and the American Academy of Pain Medicine Center of Excellence
- Worked alongside former Denver Broncos and Colorado Rockies team physicians at Advanced Orthopedics and Sports Medicine Specialists, P.C.
- Took Orthopedic Surgery call during this period
- Served on staff at the Mayo Clinic in Eau Claire, Wisconsin through the Pain Clinic of Northwestern Wisconsin in a high-volume, anesthesia-based interventional pain practice
- Led the turnaround of the HealthEast Spine Center as Medical Director and Service Line Medical Director, increasing clinical volume by more than an order of magnitude in two years
- Served for seven years as an interventional physiatrist at Midwest Spine and Brain Institute, treating complex spine and pain patients
- Co-founded Hypercharge Health, a center focused on FDA-cleared Class IV laser applications
- Double board-certified physician
- Provides clinical expertise to the medical–legal community
- Member of the Society for Brain Mapping and Therapeutics (SBMT) and former Board of Directors member
- SBMT is a NASA spinout think tank and legacy of President Obama’s Brain Initiative
- Participated in successful advocacy efforts resulting in a $500 million U.S. Department of Commerce Tech Park Initiative
- Represented the United States delegation to Neuroscience 20 (Neuro20) meetings in:Buenos Aires, Argentina
- Osaka, Japan
- New Delhi, India
- Co-authored internationally recognized think tank papers on the global burden of neurological disease
- Member of the Commonwealth Entrepreneur’s Club
- Co-founder of InSitu Biologics
- Co-patented a hyaluronic-based drug delivery platform designed to reduce opioid consumption
- InSitu Biologics has partnered with the Mayo Clinic to develop applications for cancer therapeutic delivery
- Founder of Acies Medical, addressing needle-related risks including Medicare Never Events such as inadvertent embolism
- Leads development of safer injection technologies across medical and aesthetic applications
- Acies Medical partners include:MedTech Makers Lab
- Medilink Midlands Venture Builder, United Kingdom National Health Service
- Focused on improving safety across the estimated $40+ billion global needle-use market
- Board member of Kinuu, a gamified occupational therapy platform for autism, Asperger’s, ADHD, and dyslexia
- Kinuu’s home-based therapy platform, Brainyact, aims to reduce caregiver burden and access barriers
- Preliminary Kinuu data shows 22–26% improvement across six developmental domains
- Blue Cross Blue Shield of Minnesota is actively engaging with Kinuu as a covered modality
- Board of Directors member at Thera Clean, developers of oxygen microbubble technology
- Technology repurposed from cardiac imaging to wound care and dermatologic applications
- Case studies from Northwestern University Department of Dermatology demonstrated improvement in severe ichthyosis
- Findings presented at the Mayo Clinic Wound Symposium (February 2025)
- Thera Clean is FDA registered for human use, with studies underway for epidermolysis bullosa
- Advisor to Niraxx, a Harvard-founded photobiomodulation company
- Company leadership includes Joshua Chen (CEO) and Dr. Paolo Cassano (Massachusetts General Hospital)
- Niraxx developed patented photobiomodulation textiles integrated directly into clothing
- Evidence-supported applications include mental health, neurodegenerative disease, fertility, soft tissue pain, and performance recovery
- Advisor to Neuro20, an FDA-cleared functional electrical stimulation technology with five indications and Medicare reimbursement
- Neuro20 developed by DJ Schmidt, former U.S. Marine Special Forces and CIA contractor
- Ongoing clinical use at Shirley Ryan Ability Lab, Johns Hopkins, and Shepherd Rehabilitation Center
- Early case data demonstrated restored ambulation in an individual with multiple sclerosis following structured use
- Partnered with DueDash Investment Management Platform, connecting startups with investors
- Focused on advancing non-pharmacologic, socially impactful healthcare technologies
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