1. Deep Tissue Penetration
Near-infrared (NIR) light in the range of 800 nm to 1100 nm is known for its ability to penetrate deeper into biological tissues compared to visible light or other wavelengths of infrared light. The 1070 nm wavelength falls within this NIR spectrum, allowing it to reach deeper brain tissues, which is crucial for treating conditions related to the brain or the central nervous system. Because the skull and scalp present optical barriers, deeper-penetrating wavelengths may be advantageous when designing transcranial photobiomodulation devices.
2. Interaction with Cytochrome c Oxidase (CCO)
One of the primary mechanisms of action for PBM is the absorption of NIR light by cytochrome c oxidase (CCO), a key enzyme in the mitochondrial electron transport chain responsible for cellular energy production (ATP). The absorption peaks for CCO are in the NIR region, and while the most commonly cited peaks are around 810 nm, 830 nm, and 904 nm, research suggests that wavelengths throughout the NIR spectrum can be beneficial. The effectiveness of a specific wavelength, like 1070 nm, can depend on various factors including the target tissue depth and the specific application.
Why 1070nm for Brain Photobiomodulation?
When designing photobiomodulation devices for brain applications, wavelength selection must balance:
Penetration depth
Biological interaction
Practical device engineering considerations
1070nm sits within the deeper-penetrating end of the NIR spectrum and is selected based on these combined scientific and practical considerations.
Summary
Neuronic uses the 1070nm near-infrared wavelength because:
It falls within the optical window known for deeper tissue penetration
It interacts with mitochondrial enzymes involved in ATP production
It is suitable for applications involving deeper brain tissues
Wavelength selection in photobiomodulation depends on the intended application, tissue depth, and overall device design.
